Blood Testing

Electric is the Future

A revolutionary diagnostic platform utilizing proprietary electrical sensing enabled by microfluidics, machine learning, and aptamers

Disrupting point-of-care (POC) blood testing with the first and best-in-class platform

Multi-analyte

Electrical detection + aptamers + proprietary chemistry + data science enables detection of cells, electrolytes, small molecules, and proteins

Low-cost

Chronus technology enables low-cost testing via its platform and consumables

No sample prep

Whole blood. CLIA-waived - does not require a trained lab technician

No operator intervention
No centrifuge
Modular

Fits any clinical environment

Urgent cares
Infusion Clinics
Skilled Nursing Facilities
Retail Clinics
Primary Care

Delivering all common blood tests at point-of-care with results in 15 minutes at a low-cost

There is no commercial analyzer today that can do cell assays, chemistry and immunoassay (multi-analyte) on the same platform due to the technology complexity and cost. Multi-analyte data is required for clinical decision making.

Cell assay
  • Cell counting
  • Cell differentiation
Chemistry and Immunoassay
  • Electrolyte
  • Small molecule
  • Protein

Electrical

is the Future

Re-engineering a revolutionary diagnostic platform using proprietary electrical sensing approach combined with a microfluidic sensor, machine learning, and unique aptamer technology

The Electrical System

In development. Not available for commercial sale.

System
Modular platform design

A modular platform allows one or many modules to run tests simultaneously to increase test throughput.

Electrical detection: Cell assay
Electrical detection: Chemistry
Electrical detection: Immunoassay
Chronus Health Blood testing device
Chronus Health Blood testing device in context
Multiple Chronus Health Blood testing device

Consumables
Single-use Cartridge

Cartridge with microfluidic sensor + buffer + reagent

No pipette tips
Single consumable
Label-free CBC
No plasma separation
No monolayer reagent
Self contained waste
Multiple Chronus Health Blood Test cartridges from above
Multiple Chronus Health Blood Test cartridges
Chronus Health Blood Test cartridge with blood test tube in context

Cell Assay Technology

100% electrical detection
No sample preparation
Enables miniaturization and low-cost manufacturing

A single disposable self-contained cartridge

The cartridge includes the buffer, mixing, and waste reservoirs. No additional consumables

Chronus Health Blood Test CBC Cartridge
Multiplexed label free electrical detection

Proprietary sensors and algorithms using whole blood. Simple mixing with buffer needed for cell counting

Chemistry & Immunoassay
Technology

Electrical detection for each analyte is done using an analyte-specific sensing layer chemistry deposited on electrodes. A separate electrode set is used for each measured analyte.

No sample preparation

Uses whole blood for electrolytes, small molecules, and proteins

Multiplexed electrical detection

Multiple analyte concentration is measured simultaneously current or voltage change

Chronus Health Blood Test CMP Cartridge
Analyte-sensitive layers

Each electrode has layers that interact specifically with the electrolyte, small molecule or protein to produce an electrical signal

Revolutionary protein detection technology

Analyte sensing layer combines industry-standard methods with proprietary methods and chemistry

Breakthrough electrical sensors

No lysis
No reagent bottles
No sample prep
No waste bottles
No complex optics

Chronus best-in-class Aptamer Protein detection technology

Our electrochemical aptamer-based assay uses a single-stranded DNA instead of antibodies

Check mark
Powers the Chronus Health protein assay
Check mark
Higher specificity and reliability vs. antibodies
Check mark in a square
Lower assay cost by chemically synthesizing in large quantities

We use custom aptamers selected in a blood matrix

130+ proprietary aptamer sequences and structure selected and identified for 13 targets from a library of 2^15 DNA sequences

Single aptamers with the highest specificity and sensitivity are further down-selected for use with each analyte on the Chronus Health platform.

Board

Anand Parikh
Anand Parikh
CEO / Co-Founder
10+ years in the medical device industry. Portfolio executive, private equity
Ashish Jagtiani, PhD
Ashish Jagtiani, PhD
CTO / Co-Founder
6+ years with IBM. Expertise in microfluidics, nanofabrication, and semiconductor devices
Ajit Singh, PhD
Ajit Singh, PhD
Executive Chairman
30+ years in the diagnostics industry. CEO of global corporation and startup. Partner, Venture Capital
Rishi Reddy
Rishi Reddy
Tarsadia Investments
Ryan Flynn, PhD
Ryan Flynn, PhD
Savantus Ventures
Chronus Health CEO Anand Parikh
Anand Parikh
CEO / Co-Founder
Chronus Health CTO Ashish Jagtiani
Ashish Jagtiani, PhD
CTO / Co-Founder
Chronus Health Executive Chairman Ajit Singh
Ajit Singh, PhD
Executive Chairman
Chronus Health Board Member Series A Lead Rishi Reddy
Rishi Reddy
Board Member
Not shown on live site
Left arrow
Right arrow

Advisors

Andrew Cleeland
Andrew Cleeland
CEO, Fogarty Innovation
Ceasar Djavaherian, MD
Ceasar Djavaherian, MD
Co-Founder, Carbon Health
Chuck Hall
Chuck Hall
Former National Group President, HCA Healthcare
Eric Grace
Eric Grace
Former System Engineering, Beckman Counter (Danaher)
Gary Keeler
Gary Keeler
Former President of Sales and Marketing at McKesson Medical
Hywel Morgan, PhD
Hywel Morgan, PhD
Professor of Bioelectronics, University of Southampton
Mike Regan
Mike Regan
Chief Innovation Officer at Fogarty Institute for Innovation
Robert Raynor, PhD
Robert Raynor, PhD
Former Business Development Executive, Danaher
Zach Edmonds, MD
Zach Edmonds, MD
Adjunct Professor of Medicine, Stanford University
Robert Raynor
Business Development Executive - Medical Diagnostics, Danaher Corp
Maria Vergara-Lluri, MD
Assistant Professor, Pathology, USC
Mike Regan
Chief Innovation Officer at Fogarty Institute for Innovation
Mike Regan
Chief Innovation Officer at Fogarty Institute for Innovation
Left Arrow
Right Arrow